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Marcella Coronnello Selected Research

pirarubicin

6/2019Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug resistance (MDR) modulators.
3/2018Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents.
11/2014Multidrug resistance (MDR) reversers: High activity and efficacy in a series of asymmetrical N,N-bis(alkanol)amine aryl esters.
1/2013New structure-activity relationship studies in a series of N,N-bis(cyclohexanol)amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance (MDR).
2/2010Structure-activity relationships studies in a series of N,N-bis(alkanol)amine aryl esters as P-glycoprotein (Pgp) dependent multidrug resistance (MDR) inhibitors.
2/2009N,N-bis(cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors.

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Marcella Coronnello Research Topics

Disease

11Neoplasms (Cancer)
02/2021 - 04/2002
6Acute Erythroblastic Leukemia (Erythroleukemia)
06/2019 - 02/2009
3Breast Neoplasms (Breast Cancer)
01/2021 - 03/2017
1Myeloid Leukemia (Leukemia, Myelocytic)
06/2020
1Hypoxia (Hypoxemia)
06/2020
1Neoplasm Metastasis (Metastasis)
01/2020
1Leukemia
06/2019
1Colonic Neoplasms (Colon Cancer)
01/2016
1Carcinoma (Carcinomatosis)
09/2006

Drug/Important Bio-Agent (IBA)

7Doxorubicin (Adriamycin)FDA LinkGeneric
06/2020 - 02/2009
6pirarubicinIBA
06/2019 - 02/2009
3Antineoplastic Agents (Antineoplastics)IBA
02/2021 - 04/2002
2Biological ProductsIBA
01/2021 - 07/2005
2Liposomes (Liposome)IBA
01/2016 - 04/2014
2artemisinin (artemisinine)IBA
01/2016 - 04/2014
2GoldIBA
09/2006 - 04/2002
1ChloridesIBA
02/2021
1tariquidar (XR9576)IBA
02/2021
1BerberineIBA
02/2021
1Biomarkers (Surrogate Marker)IBA
01/2021
1Pharmaceutical PreparationsIBA
01/2021
1Adrenergic Agents (Adrenergic Drugs)IBA
06/2020
13- (2- ethylphenoxy)- 1- (1,2,3,4- tetrahydronaphth- 1- ylamino)- 2- propanol oxalateIBA
06/2020
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
04/2020
1Adenosine Triphosphate (ATP)IBA
01/2020
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2020
1Carrier Proteins (Binding Protein)IBA
06/2019
1EstersIBA
06/2019
1multidrug resistance-associated protein 1IBA
06/2019
1Proteins (Proteins, Gene)FDA Link
06/2019
1Poly(amidoamine)IBA
03/2017
1Dendrimers (Dendrons)IBA
03/2017
1Biological FactorsIBA
01/2016
1IronIBA
01/2016
1Transferrin (beta 2 Transferrin)IBA
01/2016
1IonsIBA
01/2016
1Transferrin Receptors (Transferrin Receptor)IBA
01/2016
1artenimol (dihydroartemisinin)IBA
04/2014
1polyethylene glycol 2000IBA
04/2014
1CholesterolIBA
04/2014
1LigandsIBA
09/2006
12,2'-Dipyridyl (2,2 Bipyridine)IBA
09/2006
1Oxaliplatin (Eloxatin)FDA LinkGeneric
10/2005
1Cisplatin (Platino)FDA LinkGeneric
10/2005

Therapy/Procedure

1Adjuvant Chemotherapy
01/2021
1Neoadjuvant Therapy
01/2021
1Drug Therapy (Chemotherapy)
01/2016
1Therapeutics
01/2016